Product Description

OZF Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES14345-50, ES14345-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human OZF AA range: 3-53

Isotype: IgG

Target: OZF

Specificity: This antibody detects endogenous levels of OZF at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Liver, skeletal and heart muscle, mammary cells, Very low levels in brain, lung, placenta and kidney, Strongly overexpressed in many pancreas and colorectal cancers, Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas, Overexpressed in 80% of colorectal cancers,

Molecular Weight (Da): 32kD

Function: Miscellaneous: Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers
PTM: Sumoylated
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 10 C2H2-type zinc fingers
Subunit: Binds DNA. Interacts with SUMO conjugating enzyme UBC9/UBE2I. Interacts with the telomeric protein TERF2IP
Tissue Specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: ZNF146 OZF

Protein Name: OZF

Mouse Gene ID: 26465

Mouse SwissProt Number: Q8BQN6

Research Use Only