p19ARF Rabbit pAb - A24462

p19ARF Rabbit pAb Sizes: 20μL, 100μL Catalogue Numbers: A24462-20, A24462-100 Citations, Manuals and MSDS Available upon request. Background: Enables MDM2/MDM4 family protein binding activity; enzyme inhibitor activity; and protein N-terminus binding activity. Involved in several processes, including negative regulation of lymphocyte proliferation; positive regulation of apoptotic process; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including negative regulation of cellular protein metabolic process; negative regulation of mammary gland epithelial cell proliferation; and positive regulation of apoptotic process involved in mammary gland involution. Located in cytoplasm and granular component. Part of protein-containing complex. Is expressed in several structures, including bone marrow; central nervous system; dorsal root ganglion; eye; and testis. Human ortholog (s) of this gene implicated in several diseases, including breast cancer (multiple) ; carcinoma (multiple) ; hematologic cancer (multiple) ; melanoma (multiple) ; and nervous system cancer (multiple). Orthologous to human CDKN2A (cyclin dependent kinase inhibitor 2A). Category: Polyclonal Antibodies Applications: WB, ELISA Cross-reactivity: Human Protein Weight: 19kDa Observed Molecular Weight: 17kDa Immunogen: Synthetic peptide Species: Mouse GeneID: 12578 SWISS: Q64364 Alternate Names: Arf; MTS1; Pctr1; p19ARF; p19; ARF-INK4a; INK4a-ARF; Ink4a/Arf; Source: Rabbit Isotype: IgG Purity: Affinity purification Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3. Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. NCBI Alias: CDKN2A Research Use Only