P2RY12 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1710-20, A1710-100
Citations, Manuals and MSDS Available upon request.
Background: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
Category: Polyclonal Antibodies
Applications: WB, IF-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 39kDa
Observed Molecular Weight: 45kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 64805
SWISS: Q9H244
Alternate Names: HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T (AC) ; P2Y (AC) ; P2Y (12) R; P2Y (ADP) ; P2Y (cyc) ; P2RY12
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Neuroscience.
NCBI Alias: P2RY12
Research Use Only