P2Y12 Polyclonal Antibody - BT-AP12628

P2Y12 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12628-20, BT-AP12628-50, BT-AP12628-100

Citations, Manuals and MSDS Available upon request.

Background: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Research Areas: Neuroscience; Signal transduction

Target Protein: P2RY12

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: P2Y purinoceptor 12

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9H244; Mouse: Q9CPV9; Rat: Q9EPX4

Synonyms: P2Y purinoceptor 12;P2Y12;ADP-glucose receptor;ADPG-R;P2T;AC;P2Y;AC;P2Y;cyc;P2Y12 platelet ADP receptor;P2Y;ADP;SP1999

GeneID: Human: 64805

Research Use Only