P3H2 Polyclonal Antibody - BT-AP12646

P3H2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12646-20, BT-AP12646-50, BT-AP12646-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Areas: Neuroscience; Signal transduction

Target Protein: LEPREL1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Prolyl 3-hydroxylase 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8IVL5; Mouse: Q8CG71; Rat: Q4KLM6

Synonyms: Prolyl 3-hydroxylase 2;EC 1.14.11.7;Leprecan-like protein 1;Myxoid liposarcoma-associated protein 4

GeneID: Human: 55214

Research Use Only