Product Description

P4HB Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46178-50, BS46178-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant mμltifunctional enzyme that belongs to the protein disμlfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disμlfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disμlfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, ICC/IF, FC

Alternate Names: DSI, GIT, PDI, PHDB, PDIA1, PO4DB, PO4HB, PROHB, CLCRP1, ERBA2L, P4Hbeta

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human P4HB

Dilution: WB: 1:1000-1:5000 IHC: 1:200 ICC/IF: 1:20-1:100 FC: 1:20-1:100

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 57 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P07237

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only