PAPP1 Polyclonal Antibody - BT-AP12770

PAPP1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12770-20, BT-AP12770-50, BT-AP12770-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.

Research Areas: Cardiovascular; Cell biology

Target Protein: PAPPA

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Pappalysin-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13219; Mouse: Q8R4K8

Synonyms: Pappalysin-1;EC 3.4.24.79;Insulin-like growth factor-dependent IGF-binding protein 4 protease;IGF-dependent IGFBP-4 protease;IGFBP-4ase;Pregnancy-associated plasma protein A;PAPP-A

GeneID: Human: 5069

Research Use Only