PARP9 Polyclonal Antibody - BT-AP12799

PARP9 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12799-20, BT-AP12799-50, BT-AP12799-100

Citations, Manuals and MSDS Available upon request.

Background: Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,miscellaneous:Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration.,Contains 1 PARP catalytic domain.,Contains 2 Macro domains.,subunit:Interacts with BBAP.,tissue specificity:Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form.,

Research Areas: Cancer; Epigenetics and nuclear signaling

Target Protein: PARP9

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Poly [ADP-ribose] polymerase 9

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8IXQ6; Mouse: Q8CAS9

Synonyms: Poly [ADP-ribose] polymerase 9;PARP-9;EC 2.4.2.30;ADP-ribosyltransferase diphtheria toxin-like 9;ARTD9;B aggressive lymphoma protein

GeneID: Human: 83666

Research Use Only