PCNA Monoclonal Antibody (12D10), AbFluor™ 350 Conjugated
Sizes: 50μL, 100μL
Catalogue Number: RA11810-50, RA11810-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
Store At/In: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
Recommended Dilutions: Optimal working Dilutions should be determined experimentally by the investigator. Suggested starting Dilutions are as follows: IHC: 1:200, IF 1:200.
Alternative Names: PCNA
Background: proliferating cell nuclear antigen(PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],
Applications: WB; IF/ICC; IHC-p
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 5111
SWISS: P12004
Source: Mouse
Research Use Only