PDC10 Polyclonal Antibody - BT-AP12857

PDC10 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12857-20, BT-AP12857-50, BT-AP12857-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Research Areas: Cell biology; Developmental biology; Neuroscience; Signal transduction

Target Protein: PDCD10

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Programmed cell death protein 10

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9BUL8; Mouse: Q8VE70; Rat: Q6NX65

Synonyms: Programmed cell death protein 10;Cerebral cavernous malformations 3 protein;TF-1 cell apoptosis-related protein 15

GeneID: Human: 11235

Research Use Only