PDE1A Polyclonal Antibody - BT-AP12868

PDE1A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12868-20, BT-AP12868-50, BT-AP12868-100

Citations, Manuals and MSDS Available upon request.

Background: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001

Research Areas: Signal transduction

Target Protein: PDE1A

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P54750; Mouse: Q61481

Synonyms: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A;Cam-PDE 1A;EC 3.1.4.17;61 kDa Cam-PDE;hCam-1

GeneID: Human: 5136

Research Use Only