PDE1B Polyclonal Antibody - BT-AP12869

PDE1B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12869-20, BT-AP12869-50, BT-AP12869-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Areas: Signal transduction

Target Protein: PDE1B

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q01064; Mouse: Q01065; Rat: Q01066

Synonyms: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B;Cam-PDE 1B;EC 3.1.4.17;63 kDa Cam-PDE

GeneID: Human: 5153

Research Use Only