PDE5A Polyclonal Antibody - BT-AP12876

PDE5A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12876-20, BT-AP12876-50, BT-AP12876-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5andapos;-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Research Areas: Cancer; Cardiovascular; Cell biology; Metabolism; Signal transduction

Target Protein: PDE5A

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: cGMP-specific 3',5'-cyclic phosphodiesterase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O76074; Mouse: Q8CG03; Rat: O54735

Synonyms: cGMP-specific 3',5'-cyclic phosphodiesterase;EC 3.1.4.35;cGMP-binding cGMP-specific phosphodiesterase;CGB-PDE

GeneID: Human: 8654

Research Use Only