PE Anti-Mouse CD366/Tim-3 Antibody [RMT3-23] - E-AB-F1192UD

PE Anti-Mouse CD366/Tim-3 Antibody [RMT3-23]

Size: 100μg

Catalogue Number: E-AB-F1192UD-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD366/Tim-3

Target Synonym: TIM3, TIMD3, HAVcr-2, TIMD-3,

Conjugation: PE

Host: Rat

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Rat IgG2a, κ

Clone No.: RMT3-23

UNIProt ID: Q8VIM0

Background: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09833D

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 84868

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag