PE Rabbit anti-Human CD220 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A28239-100, A28239-200, A28239-500
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 156 kDa
Species: Human
GeneID: 3643
SWISS: P06213
Alternate Names: HHF5; CD220
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Protein phosphorylation, Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, AMPK Signaling Pathway, Insulin Receptor Signaling Pathway, Endocrine and metabolic diseases, Diabetes, Immunology Inflammation, CDs, Neuroscience, Cardiovascular, Heart, Cardiovascular diseases, Heart disease
NCBI Alias: INSR
Modifications: Unmodified
Conjugate: PE. Ex:565nm. Em:574nm.
Clone Number Info: ARC77158
Research Use Only