PE Rabbit anti-Human CD262/DR5/TRAILR2 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A26741-100, A26741-200, A26741-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 48kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 8795
SWISS: O14763
Alternate Names: DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Growth factors, Death Receptor Signaling Pathway, Immunology Inflammation, CDs, NF-kB Signaling Pathway
NCBI Alias: TNFRSF10B
Modifications: Unmodified
Conjugate: PE. Ex:565nm. Em:574nm.
Clone Number Info: ARC61149
Research Use Only