PE Rabbit anti-Human IL-17RA/CD217 Monoclonal Antibody - A27411

PE Rabbit anti-Human IL-17RA/CD217 Monoclonal Antibody

Sizes: 100T, 2 x 100T, 5 x 100T

Catalogue Numbers: A27411-100, A27411-200, A27411-500

Citations, Manuals and MSDS Available upon request.

Background: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category: Monoclonal Antibodies

Application: FC

Cross Reactivity: Human

Protein Weight: 96kDa Immunogen: Recombinant protein (or fragment).

Species: Human

GeneID: 23765

SWISS: Q96F46

Alternate Names: CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.

Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume

Research Areas: Immunology Inflammation, CDs, Cytokines, Interleukins, Cell Intrinsic Innate Immunity Signaling Pathway

NCBI Alias: IL17RA

Modifications: Unmodified

Conjugate: PE. Ex:565nm. Em:574nm.

Clone Number Info: ARC72068

Research Use Only