PFK-2 liv Polyclonal Antibody - BT-AP07090

PFK-2 liv Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07090-20, BT-AP07090-50, BT-AP07090-100

Citations, Manuals and MSDS Available upon request.

Background: PFKFB1 encodes a member of the family of bifunctional 6-phosphofructo-2-kinase: fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for PFKFB1.

Research Areas: Signal Transduction; Metabolism

Target Protein: PFKFB1

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PFK-2 liv Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 54681

UniProt Accession: Human: P16118; Mouse: P70266; Rat: P07953

Synonyms: PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme

GeneID: Human: 5207; Mouse: 18639; Rat: 24638

Research Use Only