PHLP1 Polyclonal Antibody - BT-AP12999

PHLP1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12999-20, BT-AP12999-50, BT-AP12999-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Research Areas: Cancer

Target Protein: PHLPP1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PH domain leucine-rich repeat-containing protein phosphatase 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O60346; Mouse: Q8CHE4; Rat: Q9WTR8

Synonyms: PH domain leucine-rich repeat-containing protein phosphatase 1;EC 3.1.3.16;Pleckstrin homology domain-containing family E member 1;PH domain-containing family E member 1;Suprachiasmatic nucleus

GeneID: Human: 23239

Research Use Only