Product Description

Phospho-ABCA1 (Ser2054) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43376-50, BS43376-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecμles across extra- and intracellμlar membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in mμlticellμlar eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellμlar lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ICC/IF

Alternate Names: TGD, ABC1, CERP, ABC-1, HDLDT1, HPALP1, HDLCQTL13

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser2054 of human ABCA1

Dilution: WB: 1:2000-1:10000 ICC/IF: 1:100

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 254 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95477

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only