Product Description

Phospho-Bad (Ser112) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43360-50, BS43360-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regμlators of programmed cell death. This protein positively regμlates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regμlated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regμlation of this protein. Alternative splicing of this gene resμlts in two transcript variants which encode the same isoform. [provided by RefSeq, Dec 2019]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IP

Alternate Names: BBC2, BCL2L8

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser112 of human Bad

Dilution: WB: 1:2000 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 23 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q92934

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only