Product Description

Phospho-Cytokeratin 8 (Ser23) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43082-50, BS43082-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellμlar structural integrity and also functions in signal transduction and cellμlar differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF, IP

Alternate Names: K8, KO, CK8, CK-8, CYK8, K2C8, CARD2

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser23 of human Cytokeratin 8

Dilution: WB: 1:2000-1:10000 IHC: 1:20 ICC/IF: 1:20 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 54 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P05787

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only