Phospho-HDAC8-S39 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: AP0360-20, AP0360-100
Citations, Manuals and MSDS Available upon request.
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications: Phosphorylated Antibodies
Applications: IF/ICC
Cross-reactivity: Human
Protein Weight: 42kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 55869
SWISS: Q9BY41
Alternate Names: HD8; WTS; RPD3; CDA07; CDLS5; KDAC8; MRXS6; HDACL1; Phospho-HDAC8-S39
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: IF/ICC, 1:100 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Immunology Inflammation, NF-kB Signaling Pathway, Stem Cells, Cardiovascular, Heart, Hypertrophy.
NCBI Alias: HDAC8
Research Use Only