Product Description

Phospho-IGF1 Receptor (Tyr1166) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43469-50, BS43469-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This receptor binds insμlin-like growth factor with a high affinity. It has tyrosine kinase activity. The insμlin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IP

Alternate Names: IGFR, CD221, IGFIR, JTK13

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding
Tyr1166 of human INSR/IGF-1R

Dilution: WB: 1:1000 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 95 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P08069

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only