Phospho-MAP3K5-T845 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: AP1215-20, AP1215-100
Citations, Manuals and MSDS Available upon request.
Background: Enables MAP kinase kinase kinase activity and protein kinase binding activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; positive regulation of JNK cascade; and positive regulation of cell death. Acts upstream of or within several processes, including cellular response to reactive nitrogen species; intracellular signal transduction; and positive regulation of MAPK cascade. Predicted to be located in cytoplasm. Predicted to be part of IRE1-TRAF2-ASK1 complex and protein kinase complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; heart; and sensory organ. Human ortholog (s) of this gene implicated in Huntington's disease. Orthologous to human MAP3K5 (mitogen-activated protein kinase kinase kinase 5).
Applications: Phosphorylated Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 155kDa
Observed Molecular Weight: 155kDa
Immunogen: Synthetic peptide
Species: Mouse
GeneID: 26408
SWISS: O35099
Alternate Names: ASK; ASK1; Mekk5; MAPKKK5; 7420452D20Rik; Phospho-MAP3K5-T845
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: Map3k5
Research Use Only