Product Description

Phospho-PDGF Receptor beta (Tyr771) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43247-50, BS43247-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regμlated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing resμlts in a mμltitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IP

Alternate Names: Pdgfr, CD140b, PDGFR-1, AI528809

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding
Tyr771 of human PDGF Receptor beta

Dilution: WB: 1:1000 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 190 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P05622

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only