Phospho-Smad5-S463/S465 Rabbit pAb - AP1319

Phospho-Smad5-S463/S465 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: AP1319-20, AP1319-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

Applications: Phosphorylated Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 52kDa

Immunogen: Synthetic peptide

Species: Human

GeneID: 4090

SWISS: Q99717

Alternate Names: DWFC; JV5-1; MADH5; Phospho-Smad5-S463/S465

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, Cell Biology Developmental Biology, TGF-b-Smad Signaling Pathway, ESC Pluripotency and Differentiation, Stem Cells.

NCBI Alias: SMAD5

Research Use Only