PIP5KIγ Polyclonal Antibody-BS5857

PIP5KIγ Polyclonal Antibody

Catalogue Numbers: BS5857-50, BS5857-100

Sizes: 50µl, 100µl

Alternative Name: Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; PtdIns(4)P-5-kinase 1 gamma; Phosphatidylinositol 4-phosphate 5-kinase type I gamma; PIP5KIgamma; PIP5K1C; KIAA0589; PIP5KI γ; PIP5KI-γ

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O60331

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking and cytoskeletal organization. The PIPK family is divided into type I, type II and type III. Each type of the PIPK family phosphorylates distinct substrates. They contain an activation loop, which determines their enzymatic specificity and subcellular targeting. The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I α, β and γ, which are characterized by phosphorylating PI4P on the 5-hydroxyl. PIPK I α, designated PIPK I β in mouse, is expressed in brain tissue. PIPK I β, designated PIPK I α in mouse, is also called STM7. PIPK I γ has two variants produced by alternative splicing which are expressed in lung, brain and kidneys.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PIP5KIγ polyclonal antibody detects endogenous levels of PIP5KIγ protein.

Bioworld Molecular Weight: ~ 73, 87 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of PIP5KIγ polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: Raw264.7 cell lysate
Lane 3: PC12 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 346-391 of Human PIP5KIγ.

Conjugate: Unconjugated

Modification: Unmodified