PKCβ1 Polyclonal Antibody-BS91082

PKCβ1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91082-50, BS91082-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P05771(Human) P68404(Mouse) P68403(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC FC

All Applications: WB:1:500
IHC:1:50-1:200
FC:1:50-1:100

Background: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoformsandν. Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: PKCβ1 polyclonal antibody detects endogenous levels of PKCβ1 protein.

Bioworld Molecular Weight: 77 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PKC beta 1 on L929 cell using anti-PKC beta 1 antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PKC beta 1 antibody. Counter stained with hematoxylin.

Alternative Name: PKC-B, PKC-beta, PRKCB, PKCB, PRKCB1, BTN6, BTNL11, MGC26137, MOG alpha 5, MOG alpha 6, MOG AluA, MOG AluB, MOG, MOG Ig AluB, MOG, MOGIG2, Myelin oligodendrocyte glycoprotein, Myelin-oligodendrocyte glycoprotein, NRCLP7,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified