Product Description

PKCμ Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91086-50, BS91086-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q15139(Human) Q62101(Mouse) Q9WTQ1(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB:1:500-1:2,000

Background: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PKC mu on different cell lysate using anti-PKC mu antibody at 1/1,000 dilution. Positive control： Lane 1: Hela Lane 2: Mouse kidney Lane 3: PC12

Bioworld Molecular Weight: 102 kDa

Specificity: PKCμ polyclonal antibody detects endogenous levels of PKCμ protein.

Alternative Name: PRKD1, PKD, PKD1, PRKCM, KPCD1, nPKC D1, nPKC mu, nPKC-D1, nPKC-mu, nPKCD1, nPKCmu, PKC, PKC MU, PKCM, PKCmu, PKD 1, PKD, PKD1, PRKCM, PRKD 1, Prkd1, Protein kinase C mu, Protein kinase C mu type, Protein kinase D, Protein kinase D1, Serine/threonine protein kinase D1, Serine/threonine-protein kinase D1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified