Product Description

PKC β (phospho Ser661) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28801-50, RA28801-100

Citations, Manuals and MSDS Available upon request.

Background: protein kinase C beta (PRKCB) Homo sapiens Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stres

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5579

Protein MW (KDa): 77

SWISS: P05771

Source: Rabbit

Research Use Only