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Placental alkaline phosphatase (PLAP) Polyclonal Antibody - E-AB-92361

Placental alkaline phosphatase (PLAP) Polyclonal Antibody - E-AB-92361

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Placental alkaline phosphatase (PLAP) Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92361-60, E-AB-92361-120, E-AB-92361-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Placental alkaline phosphatase (PLAP)

Target Synonym: ALPP; ALP; PALP; PLAP; PLAP-1; alkaline phosphatase; placental

Research Areas: Cancer, Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IP

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P05187

Background: The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human Placental alkaline phosphatase

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IP 50-1:200

Calculated MW: 57kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only