Placental alkaline phosphatase (PLAP) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A21424-20, A21424-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human
Protein Weight: 58kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 250
SWISS: P05187
Alternate Names: ALP; IAP; ALPI; PALP; PLAP; PLAP-1; Placental alkaline phosphatase (PLAP)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Stem Cells.
NCBI Alias: ALPP
Research Use Only