PLCγ2 (phospho-Tyr759) Rabbit Polyclonal Antibody - RA28878

PLCγ2 (phospho-Tyr759) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28878-50, RA28878-100

Citations, Manuals and MSDS Available upon request.

Background: phospholipase C gamma 2 (PLCG2) Homo sapiens The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 5336

Protein MW (KDa): 148

SWISS: P16885

Source: Rabbit

Research Use Only