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POLR2E Rabbit pAb - A1755

POLR2E Rabbit pAb - A1755

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POLR2E Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A1755-20, A1755-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 25kDa

Observed Molecular Weight: 26kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 5434

SWISS: P19388

Alternate Names: RPB5; XAP4; RPABC1; hRPB25; hsRPB5; POLR2E

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol,  preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Neuroscience, Neurodegenerative Diseases.

NCBI Alias: POLR2E

Research Use Only