PON3 Polyclonal Antibody - BT-AP13228

PON3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13228-20, BT-AP13228-50, BT-AP13228-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized.

Research Areas: Cardiovascular; Metabolism; Neuroscience; Signal transduction

Target Protein: PON3

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Serum paraoxonase/lactonase 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q15166; Mouse: Q62087; Rat: Q68FP2

Synonyms: Serum paraoxonase/lactonase 3;EC 3.1.1.2;EC 3.1.1.81;EC 3.1.8.1

GeneID: Human: 5446

Research Use Only