PP2A-Aβ/PR65β/PPP2R1B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24836-20, A24836-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Rat
Protein Weight: 52kDa/61kDa/66kDa/73kDa
Observed Molecular Weight: 66kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 5519
SWISS: P30154
Alternate Names: PPP2R1B; PP2A-Abeta; PR65B; protein phosphatase 2 scaffold subunit Abeta; PP2A-Aβ/PR65β/PPP2R1B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Kinase, Cell Biology & Developmental Biology, Apoptosis, Cell Cycle, Centromere, Wnt/β-Catenin Signaling Pathway.
NCBI Alias: PPP2R1B
Research Use Only