Product Description

PP2B-Aα Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11870-50, RA11870-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:A phosphoprotein + H (2) O = a protein + phosphate.,cofactor:Binds 1 Fe (3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1.,online information:Calcineurin entry,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.,

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5530

SWISS: Q08209

Source: Mouse

Research Use Only