Product Description

PP2Cε Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28947-50, RA28947-100

Citations, Manuals and MSDS Available upon request.

Background: protein phosphatase, Mg2+/Mn2+ dependent 1L (PPM1L) Homo sapiens The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: PPM1L; PP2CE; Protein phosphatase 1L; Protein phosphatase 1-like; Protein phosphatase 2C isoform epsilon; PP2C-epsilon

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 151742

Protein MW (KDa): 48

SWISS: Q5SGD2

Source: Rabbit

Research Use Only