Product Description

Proprotein Convertase 9 (PCSK9) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS71876-50, BS71876-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regμlated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellμlar matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing resμlts in mμltiple transcript variants.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-P, IF/ICC, IP

Alternate Names: PCSK9, FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthetic peptide of human Proprotein Convertase 9(PCSK9)(NP_777596.2).

Dilution: WB, 1:500 - 1:1000 IHC, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 IP, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Proprotein Convertase 9(PCSK9) polyclonal antibody detects endogenous levels of Proprotein Convertase 9(PCSK9) protein.

Molecular Weight: 80KDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8NBP7

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only