PRP8 Polyclonal Antibody - BT-AP13327

PRP8 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13327-20, BT-AP13327-50, BT-AP13327-100

Citations, Manuals and MSDS Available upon request.

Background: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

Research Areas: Epigenetics and nuclear signaling; Neuroscience

Target Protein: PRPF8

Applications: IHC-p, IF

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Pre-mRNA-processing-splicing factor 8

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q6P2Q9; Mouse: Q99PV0

Synonyms: Pre-mRNA-processing-splicing factor 8;220 kDa U5 snRNP-specific protein;PRP8 homolog;Splicing factor Prp8;p220

GeneID: Human: 10594

Research Use Only