Product Description

PSGR Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES7633-50, ES7633-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, ELISA, IHC

Alternate Names: OR51E2, PSGR, Olfactory receptor 51E2, HPRAJ, Olfactory receptor OR11-16, Prostate-specific G-protein coupled receptor

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human OR51E2. AA range:221-270

Isotype: IgG

Target: PSGR

Specificity: PSGR Polyclonal Antibody detects endogenous levels of PSGR protein.

Dilution: WB 1:500-2000, IHC-p 1:50-300, ELISA 2000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Highly expressed in the prostate (PubMed:11707321), Also expressed in spleen, liver, olfactory epithelium, retinal pigment epithelium and medulla oblongata (PubMed:29249973, PubMed:11707321, PubMed:16491480), In the retinal pigment epithelium expression is restricted to the pigment cells and choroid (at protein level) (PubMed:29249973), Expressed in epidermal melanocytes (at protein level) (PubMed:27226631),

Observed Band (KD): 35kD

Fields: Olfactory transduction

Function: Function: Odorant receptor
Similarity: Belongs to the G-protein coupled receptor 1 family
Tissue Specificity: Exclusively expressed in the prostate. Up-regulated in prostate cancers

Subcellular Location: Cell membrane, Multi-pass membrane protein Early endosome membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: OR51E2

Protein Name: Olfactory receptor 51E2

Rat Gene ID: 170816

Rat SwissProt Number: O88628

Research Use Only