PUS10 Rabbit pAb - A15962

PUS10 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A15962-20, A15962-100

Citations, Manuals and MSDS Available upon request.

Background: Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Mouse, Rat

Protein Weight: 60kDa

Observed Molecular Weight: 60kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 150962

SWISS: Q3MIT2

Alternate Names: DOBI; Hup10; CCDC139; PUS10

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Apoptosis, Caspases, Endocrine Metabolism, Mitochondrial metabolism.

NCBI Alias: PUS10

Research Use Only