Product Description

Rab 11B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES7996-50, ES7996-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: RAB11B, YPT3, Ras-related protein Rab-11B, GTP-binding protein YPT3

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human RAB11B. AA range:164-213

Isotype: IgG

Target: Rab 11B

Specificity: Rab 11B Polyclonal Antibody detects endogenous levels of Rab 11B protein.

Dilution: WB 1:500-2000, IHC-p 1:50-300

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: B-cell lymphoma, Brain, Cerebellum, Muscle,

Observed Band (KD): 28kD

Fields: Endocytosis, AMPK signaling pathway, Vasopressin-regulated water reabsorption, Influenza A

Function: Function: Possesses GTPase activity
Similarity: Belongs to the small GTPase superfamily. Rab family
Subunit: Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4

Subcellular Location: Recycling endosome membrane, Lipid-anchor, Cytoplasmic side Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Lipid-anchor, Cytoplasmic side Cytoplasmic vesicle, phagosome membrane, Lipid-anchor, Cytoplasmic side Recruited to phagosomes containing Saureus

Storage and Stability: -20°C/1 year

Gene Name: RAB11B

Protein Name: Ras-related protein Rab-11B

Mouse Gene ID: 19326

Mouse SwissProt Number: P46638

Rat Gene ID: 79434

Rat SwissProt Number: O35509

Research Use Only