Product Description

RAB14 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES11931-50, ES11931-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: RAB14

Specificity: RAB14 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Adrenal gland, B-cell lymphoma, Brain, Liver, Melanoma, Placenta, Platele

Observed Band (KD): 23kD

Fields: AMPK signaling pathway

Function: Function: May be involved in vesicular trafficking and neurotransmitter release
Similarity: Belongs to the small GTPase superfamily. Rab family

Subcellular Location: Recycling endosome Early endosome membrane, Lipid-anchor, Cytoplasmic side Golgi apparatus membrane, Lipid-anchor, Cytoplasmic side Golgi apparatus, trans-Golgi network membrane, Lipid-anchor, Cytoplasmic side Cytoplasmic vesicle, phagosome Recruited to recycling endosomes by DENND6A (PubMed:22595670) Recruited to phagosomes containing Saureus or Mtuberculosis (PubMed:21255211)

Storage and Stability: -20°C/1 year

Gene Name: RAB14

Protein Name: Ras-related protein Rab-14

Mouse SwissProt Number: Q91V41

Rat SwissProt Number: P61107

Research Use Only