Product Description

RAB7B Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46148-50, BS46148-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Controls vesicμlar trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regμlator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regμlates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regμlation of the EGF- and EGFR degradation pathway.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, FC

Alternate Names: RAB7

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human RAB7B

Dilution: WB: 1:1000 IHC: 1:20 FC: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 23 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96AH8

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only