Product Description

Rad GTPase Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3302-50, ES3302-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: similarity:Belongs to the small GTPase superfamily. RGK family.,subunit:Interacts with calmodulin preferentially to the inactive, GDP-form. Binds CAMKII which is capable of phosphorylating RAD in vitro.,tissue specificity:Skeletal and cardiac muscle, and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.,

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: RRAD, RAD, GTP-binding protein RAD, RAD1, Ras associated with diabetes

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human RAD. AA range:41-90

Isotype: IgG

Target: Rad GTPase

Specificity: Rad GTPase Polyclonal Antibody detects endogenous levels of Rad GTPase protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Most abundantly expressed in the heart, Also found in the skeletal muscle and lung, Lesser amounts in placenta and kidney, Also detected in adipose tissue, Overexpressed in muscle of type II diabetic humans,

Observed Band (KD): 33kD

Function: Similarity: Belongs to the small GTPase superfamily. RGK family
Subunit: Interacts with calmodulin preferentially to the inactive, GDP-form. Binds CAMKII which is capable of phosphorylating RAD in vitro
Tissue Specificity: Skeletal and cardiac muscle, and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans

Subcellular Location: Cell membrane

Storage and Stability: -20°C/1 year

Gene Name: RRAD

Protein Name: GTP-binding protein RAD

Mouse SwissProt Number: O88667

Research Use Only