Product Description

Rak Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3321-50, ES3321-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: FRK, PTK5, RAK, Tyrosine-protein kinase FRK, FYN-related kinase, Nuclear tyrosine protein kinase RAK, Protein-tyrosine kinase 5

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human FRK. AA range:71-120

Isotype: IgG

Target: Rak

Specificity: Rak Polyclonal Antibody detects endogenous levels of Rak protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon,

Observed Band (KD): 55kD

Function: Catalytic Activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily
Similarity: Contains 1 protein kinase domain
Similarity: Contains 1 SH2 domain
Similarity: Contains 1 SH3 domain
Tissue Specificity: Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin

Subcellular Location: Cytoplasm Nucleus Predominantly found in the nucleus, with a small fraction found in the cell periphery

Storage and Stability: -20°C/1 year

Gene Name: FRK

Protein Name: Tyrosine-protein kinase FRK

Mouse Gene ID: 14302

Mouse SwissProt Number: Q922K9

Rat Gene ID: 79209

Rat SwissProt Number: Q62662

Research Use Only