RARα Rabbit pAb - A0370

RARα Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A0370-20, A0370-100

Citations, Manuals and MSDS Available upon request.

Background: This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 51kDa

Observed Molecular Weight: 60kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 5914

SWISS: P10276

Alternate Names: RAR; NR1B1; RARalpha; RARα

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Nuclear Receptor Signaling, Nuclear hormone receptors, Cancer, Signal Transduction, Cell Biology Developmental Biology, Wnt -Catenin Signaling Pathway.

NCBI Alias: RARA

Research Use Only