Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody - E-AB-81528

Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-81528-50, E-AB-81528-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: Angiotensin II Type 1 Receptor

Target Synonym: AGTR1; AG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R

Research Areas: Cancer, Cardiovascular, Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Rabbit Monoclonal

Clone No.: R07-1I6

UNIProt ID: P30556

Background: Angiotensin II (Ang II), the main effector molecule of the renin-angiotensin system, exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1, also named as AT1R), thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone, cardiovascular function, salt and water homeostasis, AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease, from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .

Concentration: 300 μg/mL

Immunogen: A synthetic peptide of human Angiotensin II Type 1 Receptor

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification Method: Affinity Purified

Dilution: WB 1:1000-1:2000

Calculated MW: 41kDa

Observed MW: 41kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only